Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL3154012 | 0.96 | ELANE (0.56) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL28188938 | 0.87 | LMNA (0.47) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL1395475 | 0.85 | CA1 (0.47) | LMNAELANEHSD17B10GAACA1 | |
| SCHEMBL4113624 | 0.84 | AKT1 (0.55) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL609104 | 0.83 | CA1 (0.48) | LMNAMAPTELANEHSD17B10ALDH1A1 | |
| SCHEMBL777803 | 0.83 | ELANE (0.62) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL9081470 | 0.83 | LMNA (0.61) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL269329 | 0.82 | LMNA (0.80) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL17343019 | 0.81 | ELANE (0.54) | LMNAMAPTPOLBELANEHSD17B10 | |
| SCHEMBL68678 | 0.81 | LMNA (0.59) | LMNAMAPTPOLBPKMELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240374562-A1 | METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS | EPICENTRX, INC. (US) | 2024-11-14 | — | — | US | claimed |
| US-20140308260-A1 | METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS | EPICENTRX, INC. | 2014-10-16 | — | — | US | claimed |
| EP-2094292-B1 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | IKOR INC (US) | 2014-07-09 | — | — | EP | claimed |
| WO-2013052803-A2 | METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS | RADIORX, INC. (US) | 2013-04-11 | — | — | WO | claimed |
| US-20080096805-A1 | deoxygenated, endotoxin-free and stroma-free transport proteins, incapable of binding with nitric oxide, useful as substitutes for erythrocytes in mammals and for treating disorders where oxygen delivery agents are of benefit | IKOR, INC. | 2008-04-24 | — | — | US | claimed |
| US-20080096803-A1 | Carboxymethylated cross-linked tetrameric hemoglobin | IKOR, INC. | 2008-04-24 | — | — | US | claimed |
| US-4342877-A | Process for the preparation of α-halogenated cresol esters | EASTMAN KODAK COMPANY (US) | 1982-08-03 | — | — | US | claimed |
| JP-52156826-A | — | — | None | — | — | JP | disclosed |
| US-12617805-B2 | Codrug that disintegrates in intestine, preparation therefor, and use thereof | ENNOVABIO (ZHEJIANG) PHARMACEUTICALS CO., LTD. (CN) | 2026-05-05 | — | — | US | disclosed |
| US-20260062460-A1 | METHODS FOR TREATING ACUTE CORONARY SYNDROME USING APOA-1 FUSION PROTEINS | THERIPION, INC. (US) | 2026-03-05 | — | — | US | disclosed |
| US-12509501-B2 | Polynucleotides encoding APOA-1 fusion polypeptides | THERIPION, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20250287942-A1 | FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-09-18 | — | — | US | disclosed |
| US-20250257072-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES AND PRODRUG THEREOF | SHIONOGI & CO., LTD. (JP) | 2025-08-14 | — | — | US | disclosed |
| JP-S52156826-A | PREPARATION OF P-HYDROXYBENZALDEHYDE | KUREHA CHEM IND CO LTD | 1977-12-27 | — | — | JP | disclosed |
| US-4045438-A | Cephalosporin antibiotics | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1977-08-30 | — | — | US | disclosed |
| US-4031083-A | Cephalosporin antibiotics | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1977-06-21 | — | — | US | disclosed |
| US-4026887-A | Cephalosporin antibiotics | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1977-05-31 | — | — | US | disclosed |
| US-3994875-A | CEPHALOSPORINS, PENICILLINS | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1976-11-30 | — | — | US | disclosed |
| US-3993661-A | Quinone methide photograhpic reagent precursors | POLAROID CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |
| US-3948904-A | ANTIBIOTICS | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062460-A1 | METHODS FOR TREATING ACUTE CORONARY SYNDROME USING APOA-1 FUSION PROTEINS | PON1, APOB, APOL1 | LMNA 600/4885MAPT 3644/4885POLB 2437/4885 |
| US-20250287942-A1 | FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS | ACHE, BCHE, DDT | LMNA 3388/4885MAPT 1033/4885POLB 4588/4885 |
| US-12509501-B2 | Polynucleotides encoding APOA-1 fusion polypeptides | APOB, PON1, APOL1 | LMNA 419/4885MAPT 2602/4885POLB 555/4885 |
| US-20250257072-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES AND PRODRUG THEREOF | C3AR1, CYP4B1, ADORA2B | LMNA 2305/4885MAPT 4806/4885POLB 459/4885 |
| US-20240374562-A1 | METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS | HBB, HBG2, HBZ | LMNA 2548/4885MAPT 4665/4885POLB 2076/4885 |
| US-20140308260-A1 | METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS | HBB, HBG2, HBZ | LMNA 2548/4885MAPT 4665/4885POLB 2076/4885 |
| US-12617805-B2 | Codrug that disintegrates in intestine, preparation therefor, and use thereof | IRAK4, JAK1, VIP | LMNA 3587/4885MAPT 4003/4885POLB 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.