Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16622434 | 0.80 | USP2 (0.40) | USP2ALDH1A1 | |
| SCHEMBL16835486 | 0.73 | DDB1 (0.31) | — | |
| SCHEMBL30617292 | 0.70 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL15759336 | 0.65 | FFAR3 (0.38) | USP2ALDH1A1MAPK1CYP2C19CYP2D6 | |
| SCHEMBL2435817 | 0.65 | GABRD (0.31) | USP2CYP2D6 | |
| SCHEMBL16612480 | 0.65 | USP2 (0.36) | USP2ALDH1A1MAPK1CYP2C19CYP2D6 | |
| SCHEMBL24203732 | 0.64 | CYP1A2 (0.41) | USP2ALDH1A1MAPK1CYP2C19CYP2D6 | |
| SCHEMBL4738222 | 0.64 | — | — | |
| SCHEMBL16914420 | 0.64 | CRBN (0.33) | USP2ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL2069668 | 0.63 | NOS3 (0.33) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |