Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615523 | 0.75 | ALDH1A1 (0.72) | ALDH1A1MAPTMAPK1HSP90AA1NPSR1 | |
| SCHEMBL295841 | 0.65 | LMNA (0.53) | ALDH1A1MAPTNPSR1TSHRKDM4E | |
| SCHEMBL3596109 | 0.64 | TSHR (0.54) | ALDH1A1MAPTMAPK1TSHRKDM4E | |
| SCHEMBL29370283 | 0.63 | TSHR (0.71) | ALDH1A1MAPTMAPK1TSHRKDM4E | |
| SCHEMBL12172745 | 0.63 | TSHR (0.71) | ALDH1A1MAPTMAPK1TSHRKDM4E | |
| SCHEMBL286790 | 0.62 | LMNA (0.64) | ALDH1A1MAPK1TSHRTDP1 | |
| SCHEMBL5147891 | 0.62 | LMNA (0.58) | ALDH1A1MAPK1NPSR1TSHRKDM4E | |
| SCHEMBL12863501 | 0.62 | LMNA (0.46) | ALDH1A1MAPTMAPK1NPSR1TSHR | |
| SCHEMBL5355058 | 0.62 | TSHR (0.66) | ALDH1A1MAPTMAPK1TSHRKDM4E | |
| SCHEMBL8359492 | 0.62 | KMT2A (0.76) | ALDH1A1MAPTTSHRKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042685-A1 | INHIBITORS OF POLYNUCLEOTIDE REPEAT-ASSOCIATED RNA FOCI AND USES THEREOF | VALORISATION-RECHERCHE (CA) | 2015-04-02 | — | — | WO | disclosed |