Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625721 | 0.76 | KDM4E (0.38) | TSHRKDM4EALDH1A1GAAPKM | |
| SCHEMBL16617685 | 0.73 | ABCB11 (0.38) | KDM4EALDH1A1USP2CYP3A4MAPK1 | |
| SCHEMBL16715104 | 0.71 | CYP3A4 (0.44) | KMT2AUSP2CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL16723081 | 0.71 | CYP3A4 (0.44) | KMT2AUSP2CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL16715103 | 0.71 | CYP3A4 (0.44) | KMT2AUSP2CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL22031170 | 0.70 | HTT (0.40) | KDM4EALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL41669 | 0.69 | TSHR (0.63) | TSHRKDM4EALDH1A1GAAPKM | |
| SCHEMBL496658 | 0.69 | TSHR (0.57) | TSHRALDH1A1POLBTDP1APEX1 | |
| SCHEMBL21980855 | 0.68 | THRB (0.44) | ALDH1A1KMT2APOLBTDP1APEX1 | |
| SCHEMBL7198348 | 0.68 | CYP3A4 (0.46) | USP2CYP3A4MAPK1SMN1; SMN2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567277-B2 | Reagent for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9567277-B2 | Reagent for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9567277-B2 | Reagent for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-04-09 | — | — | US | disclosed |
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-04-09 | — | — | US | disclosed |
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | PPOX, CYBB, CBR3 | TSHR 2976/4885KDM4E 4434/4885ALDH1A1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.