Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21675471 | 0.76 | THRB (0.39) | THRBPOLBTDP1APEX1HTT | |
| SCHEMBL27621744 | 0.76 | APLNR (0.53) | APLNRPOLBTDP1MEN1KMT2A | |
| SCHEMBL22031170 | 0.76 | HTT (0.40) | THRBPOLBTDP1APEX1HTT | |
| SCHEMBL4003210 | 0.75 | APLNR (0.63) | APLNRALDH1A1 | |
| SCHEMBL24115974 | 0.75 | ALDH1A1 (0.42) | THRBPOLBMEN1KMT2AHSD17B10 | |
| SCHEMBL22220069 | 0.75 | THRB (0.40) | THRBPOLBTDP1APEX1HTT | |
| SCHEMBL997591 | 0.75 | THRB (0.54) | THRBPOLBTDP1APEX1HTT | |
| SCHEMBL8865449 | 0.75 | APLNR (0.56) | APLNRPOLBMEN1KMT2AHSD17B10 | |
| SCHEMBL17036908 | 0.74 | THRB (0.48) | THRBPOLBTDP1APEX1HTT | |
| SCHEMBL8150697 | 0.74 | MAPT (0.58) | HTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986557-B2 | Stealth nanoparticles | HOWARD UNIVERSITY (US) | 2024-05-21 | — | — | US | claimed |
| US-20200163884-A1 | STEALTH NANOPARTICLES | HOWARD UNIVERSITY (US) | 2020-05-28 | — | — | US | claimed |
| US-11986557-B2 | Stealth nanoparticles | HOWARD UNIVERSITY (US) | 2024-05-21 | — | — | US | disclosed |
| US-20200163884-A1 | STEALTH NANOPARTICLES | HOWARD UNIVERSITY (US) | 2020-05-28 | — | — | US | disclosed |