SCHEMBL16617843

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16018015	0.88	CYP3A4 (0.49)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL24737164	0.88	CYP3A4 (0.68)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL3930018	0.80	ALDH1A1 (0.40)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL31164538	0.79	TUBB4A (0.41)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL25189210	0.79	LTA4H (0.47)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL16389267	0.79	CYP3A4 (0.57)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL24146231	0.77	CYP3A4 (0.48)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL18793123	0.77	CYP3A4 (0.55)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL2029772	0.77	CYP3A4 (0.78)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A
	SCHEMBL9112690	0.77	CYP3A4 (0.50)	CYP3A4USP2MAPK1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.