Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16616453 | 0.98 | HPGD (0.46) | HPGDBRD4SRCMGAMAMY1A | |
| SCHEMBL9914065 | 0.79 | BRD4 (0.39) | BRD4KDM4ETDP1KDM4AKDM5C | |
| SCHEMBL22276769 | 0.77 | MIF (0.62) | HPGDBRD4GAAKDM4EMEN1 | |
| SCHEMBL17122469 | 0.71 | MIF (0.40) | HPGDBRD4KDM4ETSHRMEN1 | |
| SCHEMBL19296375 | 0.71 | CYP1A2 (0.41) | BRD4KDM4EGLATSHRKDM4A | |
| SCHEMBL1449524 | 0.71 | HPGD (0.66) | HPGDMGAMAMY1AGAASI | |
| SCHEMBL1449523 | 0.71 | HSD11B1 (0.49) | HPGDMGAMAMY1AGAASI | |
| SCHEMBL9914071 | 0.70 | MAOA (0.54) | BRD4MAPK1 | |
| SCHEMBL6133984 | 0.70 | PKM (0.43) | HPGDKDM4EGLATSHRMEN1 | |
| SCHEMBL11636011 | 0.70 | KDM4E (0.55) | HPGDKDM4EGLATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051258-A1 | CROSSLINK BREAKERS FOR PRESERVATION OF BIOLOGICAL SUBSTANCES | SPIEGEL DAVID (US) | 2015-04-09 | — | — | WO | disclosed |