SCHEMBL16618966

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28207045	0.84	KDM4E (0.64)	KDM4EUBE2NCA2CA9HTR6
	SCHEMBL19971492	0.83	KDM4E (0.43)	KDM4EUBE2NCA2CA9HDAC1
	SCHEMBL19971360	0.81	AKR1C3 (0.56)	KDM4EHDAC1NAPRTHTR6AKR1C3
	SCHEMBL16618750	0.81	KDM4E (0.43)	KDM4EUBE2NCA2CA9KMT2A
	SCHEMBL16618849	0.79	KMT2A (0.56)	KDM4EHDAC1AKR1C3AKR1C1KMT2A
	SCHEMBL18080756	0.79	KDM4E (0.67)	KDM4EUBE2NCA2CA9HTR6
	SCHEMBL16619154	0.78	KDM4E (0.44)	KDM4EUBE2NCA2HDAC1HTR6
	SCHEMBL16619142	0.78	HTR6 (0.42)	HTR6KMT2AIDE
	SCHEMBL16618784	0.77	HTR6 (0.43)	KDM4EHDAC1NAPRTHTR6AKR1C3
	SCHEMBL947412	0.75	KDM4E (0.58)	KDM4EUBE2NHTR6AKR1C3AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.