Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618750 | 0.89 | KDM4E (0.43) | KDM4EUBE2NCA2CA9PDE4A | |
| SCHEMBL16618966 | 0.83 | KDM4E (0.45) | KDM4EUBE2NCA2CA9HDAC1 | |
| SCHEMBL28207045 | 0.81 | KDM4E (0.64) | KDM4EUBE2NCA2CA9ALDH1A1 | |
| SCHEMBL19971473 | 0.79 | PDE4A (0.44) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18950229 | 0.77 | PDE4A (0.42) | KDM4EUBE2NCA2CA9PDE4A | |
| SCHEMBL19971360 | 0.74 | AKR1C3 (0.56) | KDM4EHDAC1NAPRTIDELMNA | |
| Isophthalic Acid SCHEMBL28068089 | 0.73 | AKR1C3 (0.40) | CA2CA9PDE4APDE4BPDE4C | |
| SCHEMBL19971435 | 0.73 | HTR6 (0.40) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| Isophthalic Acid SCHEMBL28068086 | 0.72 | AKR1C3 (0.39) | CA2CA9PDE4APDE4BPDE4C | |
| Isophthalic Acid SCHEMBL28068084 | 0.72 | HTR6 (0.45) | KMOCSNK2A2CSNK2BHDAC1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |