Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618849 | 0.88 | KMT2A (0.56) | AKR1C3AKR1C1LMNASMN1; SMN2KMT2A | |
| SCHEMBL16618784 | 0.84 | HTR6 (0.43) | AKR1C3AKR1C1LMNASMN1; SMN2KMT2A | |
| SCHEMBL19971365 | 0.82 | AKR1C3 (0.42) | AKR1C3AKR1C1LMNASMN1; SMN2KMT2A | |
| SCHEMBL16618966 | 0.81 | KDM4E (0.45) | AKR1C3AKR1C1KMT2AKDM4ENAPRT | |
| SCHEMBL19971462 | 0.81 | LMNA (0.43) | AKR1C3AKR1C1LMNASMN1; SMN2KMT2A | |
| SCHEMBL16619044 | 0.80 | HTR6 (0.45) | KMT2AHDAC1HTR6IDE | |
| SCHEMBL19971364 | 0.79 | HSD17B10 (0.39) | AKR1C3AKR1C1PLK1KDM4EHDAC1 | |
| SCHEMBL19971444 | 0.79 | MEN1 (0.41) | AKR1C3AKR1C1LMNASMN1; SMN2KMT2A | |
| SCHEMBL19194701 | 0.78 | LMNA (0.71) | AKR1C3AKR1C1LMNASMN1; SMN2KMT2A | |
| SCHEMBL16619142 | 0.78 | HTR6 (0.42) | KMT2AHTR6IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |