Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623287 | 0.86 | SLC22A12 (0.40) | SLC22A12MAOBALDH1A1KDM4EHPGD | |
| SCHEMBL118295 | 0.80 | SLC22A12 (0.42) | SLC22A12MAOBHIF1AEPAS1PIM1 | |
| SCHEMBL118769 | 0.80 | SLC22A12 (0.40) | SLC22A12MAOBHIF1AEPAS1PIM1 | |
| SCHEMBL22336290 | 0.79 | SLC22A12 (0.36) | SLC22A12 | |
| SCHEMBL22336151 | 0.77 | CCR4 (0.38) | SLC22A12KDM4ELMNAMEN1KMT2A | |
| SCHEMBL22336249 | 0.74 | ALDH1A1 (0.36) | SLC22A12ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16623281 | 0.74 | CYP2A6 (0.51) | MAOBALDH1A1KDM4EHPGDPDE3B | |
| SCHEMBL19970441 | 0.70 | MAOB (0.38) | MAOBPIM1ALDH1A1KDM4EHPGD | |
| SCHEMBL120165 | 0.70 | ERN1 (0.44) | MAOBHIF1APIM1ALDH1A1KDM4E | |
| SCHEMBL21230500 | 0.70 | NPC1 (0.45) | SLC22A12MAOBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857018-A1 | Treatment or prophylaxis of proliferative conditions | University Court of The University of Dundee (GB) | 2015-04-08 | — | — | EP | disclosed |