Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623261 | 0.86 | SLC22A12 (0.40) | SLC22A12MAOBHPGDCYP3A4ALDH1A1 | |
| SCHEMBL22336290 | 0.80 | SLC22A12 (0.36) | SLC22A12 | |
| SCHEMBL15200324 | 0.79 | SLC22A12 (0.43) | SLC22A12ELANEMAOBHPGDCYP3A4 | |
| SCHEMBL22336151 | 0.78 | CCR4 (0.38) | SLC22A12ELANEKDM4ELMNA | |
| SCHEMBL22336249 | 0.76 | ALDH1A1 (0.36) | SLC22A12HPGDCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL16623281 | 0.75 | CYP2A6 (0.51) | MAOBHPGDALDH1A1KDM4EGAA | |
| SCHEMBL15200325 | 0.70 | PIM1 (0.54) | HPGDALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL9981201 | 0.69 | CYP2A6 (0.56) | HPGDCYP3A4ALDH1A1TDP1HSD17B10 | |
| SCHEMBL21224351 | 0.69 | NPC1 (0.49) | SLC22A12HPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL21230516 | 0.69 | HPGD (0.47) | SLC22A12HPGDCYP3A4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857018-A1 | Treatment or prophylaxis of proliferative conditions | University Court of The University of Dundee (GB) | 2015-04-08 | — | — | EP | disclosed |