Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17849211 | 0.89 | L3MBTL1 (0.38) | BDKRB1L3MBTL1WDR91CDC7PLK4 | |
| SCHEMBL17849238 | 0.82 | L3MBTL1 (0.38) | BDKRB1L3MBTL1WDR91CDC7PLK4 | |
| SCHEMBL17849209 | 0.76 | BDKRB1 (0.35) | BDKRB1SMN1; SMN2KMT2A | |
| SCHEMBL17849208 | 0.76 | HDAC6 (0.33) | HDAC1HDAC6SMN1; SMN2KMT2A | |
| SCHEMBL17849193 | 0.74 | F10 (0.43) | PRKAA1RAB9ASMN1; SMN2F10 | |
| SCHEMBL17849190 | 0.74 | LTA4H (0.33) | NTRK1PARP1RAB9A | |
| SCHEMBL16623476 | 0.74 | — | — | |
| SCHEMBL16623450 | 0.70 | NPC1 (0.32) | — | |
| SCHEMBL16623563 | 0.69 | KMT2A (0.32) | KMT2A | |
| SCHEMBL16726665 | 0.69 | ALDH2 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857400-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |