Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623554 | 0.74 | MAPK14 (0.33) | KMT2A | |
| SCHEMBL16623476 | 0.74 | — | — | |
| SCHEMBL17849205 | 0.72 | DGAT1 (0.32) | — | |
| SCHEMBL16623477 | 0.69 | BDKRB1 (0.36) | KMT2A | |
| SCHEMBL16623507 | 0.66 | ITGA4 (0.33) | — | |
| SCHEMBL16623480 | 0.65 | MAPK14 (0.34) | KMT2A | |
| SCHEMBL16726665 | 0.63 | ALDH2 (0.33) | KMT2A | |
| SCHEMBL16623479 | 0.63 | CRBN (0.40) | — | |
| SCHEMBL16623533 | 0.63 | F10 (0.34) | — | |
| SCHEMBL16623518 | 0.63 | KMT2A (0.31) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857400-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |