Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tangeretin SCHEMBL19740 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| Tangeretin SCHEMBL23629519 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| Tangeretin SCHEMBL29549538 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL16623937 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL16623939 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL21981343 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL31237871 | 0.81 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| Tangeretin SCHEMBL28155119 | 0.80 | ALDH1A1 (0.87) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL987020 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL31238014 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150098926-A1 | Methods of Treating Hepatitis C Virus Infection | THE J. DAVID GLADSTONE INSTITUTES | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150098926-A1 | Methods of Treating Hepatitis C Virus Infection | HAVCR2, LIPC, FABP1 | ALDH1A1 908/4885MEN1 4813/4885KMT2A 3148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.