Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623938 | 0.83 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL12195283 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL16549450 | 0.77 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| Nobiletin SCHEMBL244029 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| Nobiletin SCHEMBL29374681 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| Nobiletin SCHEMBL22092292 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| Nobiletin SCHEMBL30049905 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| Nobiletin SCHEMBL30049859 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL684139 | 0.74 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL13140966 | 0.74 | TUBB4A (0.56) | ALDH1A1MEN1KMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150098926-A1 | Methods of Treating Hepatitis C Virus Infection | THE J. DAVID GLADSTONE INSTITUTES | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150098926-A1 | Methods of Treating Hepatitis C Virus Infection | HAVCR2, LIPC, FABP1 | ALDH1A1 908/4885MEN1 4813/4885KMT2A 3148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.