SCHEMBL16624919

SCHEMBL16624919

CC(C(=O)c1ccccc1)C(CC(=O)OC/C=C/c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP12 P39900 1/20 0.40
CACNA1B Q00975 4/20 0.39
KCNA5 P22460 1/20 0.38
IDO1 P14902 2/20 0.37
PAM P19021 1/20 0.37
PGR P06401 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37
KCNH2 Q12809 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
PPARG P37231 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16624928 0.93 CYP1B1 (0.41) ALDH1A1LMNASMN1; SMN2NPSR1MMP1
SCHEMBL16624924 0.91 ALDH1A1 (0.45) ALDH1A1LMNASMN1; SMN2NPSR1MMP1
SCHEMBL16624893 0.83 MEN1 (0.48) ALDH1A1LMNASMN1; SMN2NPSR1KCNA5
SCHEMBL19071506 0.81 ALDH1A1 (0.39) ALDH1A1LMNASMN1; SMN2NPSR1MMP1
SCHEMBL382512 0.80 MMP1 (0.48) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL382511 0.80 MMP1 (0.48) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL19071458 0.78 ALDH1A1 (0.38) ALDH1A1LMNASMN1; SMN2NPSR1KCNA5
SCHEMBL16624917 0.78 L3MBTL1 (0.49) ALDH1A1LMNASMN1; SMN2NPSR1MMP1
SCHEMBL16624926 0.77 KCNA5 (0.58) ALDH1A1LMNASMN1; SMN2NPSR1KCNA5
SCHEMBL16624901 0.77 F2 (0.46) ALDH1A1LMNANPSR1KCNA5PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2864284-B1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO KGAA (DE) 2017-07-05 EP disclosed
US-9458081-B2 Photolabile pro-fragrances HENKEL AG & CO. KGAA (DE) 2016-10-04 US disclosed
US-9458081-B2 Photolabile pro-fragrances HENKEL AG & CO. KGAA (DE) 2016-10-04 US disclosed
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2015-04-09 US disclosed
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2015-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES TRPA1, PSAP, CRY1 ALDH1A1 236/4885LMNA 1058/4885SMN1; SMN2 2584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.