SCHEMBL16625728

SCHEMBL16625728

Cc1ccc2c(n1)c1ccccc1n2C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.54
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
GABRA4 P48169 1/20 0.46
GABRE P78334 1/20 0.46
GABRA6 Q16445 1/20 0.46
GABRG1 Q8N1C3 1/20 0.46
GABRG3 Q99928 1/20 0.46
GABRQ Q9UN88 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
MAPT P10636 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12382861 0.82 CCR1 (0.52) GPR3MAPTRAB9AKDM4EGAA
SCHEMBL25058969 0.80 PTGER4 (0.41) MAPTL3MBTL1RAB9ANPC1KDM4E
SCHEMBL12652954 0.80 PTGER4 (0.64) GPR3GABRPGABRDGABRA1GABRB1
SCHEMBL9968067 0.79 GPR3 (0.50) GPR3GABRPGABRDGABRA1GABRB1
SCHEMBL23373469 0.77 GPR3 (0.53) GPR3GABRPGABRDGABRA1GABRB1
SCHEMBL17051458 0.77 KDM4E (0.55) L3MBTL1RAB9AKDM4EKMT2AALDH1A1
SCHEMBL17109976 0.74 GPR3 (0.54) GPR3GABRPGABRDGABRA1GABRB1
SCHEMBL9968091 0.74 GPR3 (0.44) GPR3GABRPGABRDGABRA1GABRB1
SCHEMBL9968096 0.74 GPR3 (0.44) GPR3GABRPGABRDGABRA1GABRB1
SCHEMBL9968116 0.74 PRNP (0.45) GPR3GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-15 US disclosed
US-9941422-B2 Organic photoelectric conversion element and solar cell using the same Konica Minolta, Inc. (JP) 2018-04-10 US disclosed
US-9941422-B2 Organic photoelectric conversion element and solar cell using the same Konica Minolta, Inc. (JP) 2018-04-10 US disclosed
US-9882072-B2 Solar cell and transparent electrode Konica Minolta, Inc. (JP) 2018-01-30 US disclosed
US-9882072-B2 Solar cell and transparent electrode Konica Minolta, Inc. (JP) 2018-01-30 US disclosed
US-20150221793-A1 SOLAR CELL AND TRANSPARENT ELECTRODE Konica Minolta, Inc. (JP) 2015-08-06 US disclosed
US-20150096610-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING THE SAME SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2015-04-09 US disclosed
US-20150096610-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING THE SAME SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2015-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF L1CAM, LEF1, PIEZO1 GPR3 4190/4885GABRP 4229/4885GABRD 4516/4885
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRM1, OPRD1, OXER1 GPR3 1086/4885GABRP 3893/4885GABRD 1965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.