SCHEMBL16625919

SCHEMBL16625919

C=CC(=O)OCc1ccc(-c2ccc(N(c3ccc(C)c(C)c3)c3ccc(C)c(C)c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
KCNH2 Q12809 1/20 0.35
ALDH1A1 P00352 4/20 0.33
HPGD P15428 4/20 0.33
NPC1 O15118 3/20 0.33
MAPK1 P28482 2/20 0.33
KDM4E B2RXH2 2/20 0.33
TSHR P16473 2/20 0.33
GAA P10253 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
SIRT5 Q9NXA8 1/20 0.33
MET P08581 1/20 0.33
RAB9A P51151 2/20 0.33
MAPT P10636 2/20 0.33
PSMB5 P28074 2/20 0.32
S1PR1 P21453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12550531 0.96 THRB (0.38) THRBSMN1; SMN2KCNH2ALDH1A1HPGD
SCHEMBL2602453 0.96 THRB (0.38) THRBSMN1; SMN2KCNH2ALDH1A1HPGD
SCHEMBL26531990 0.95 RAB9A (0.40) THRBALDH1A1HPGDNPC1LMNA
SCHEMBL14448401 0.93 MET (0.40) THRBSMN1; SMN2KCNH2ALDH1A1HPGD
SCHEMBL22639379 0.93 THRB (0.36) THRBSMN1; SMN2KCNH2ALDH1A1HPGD
SCHEMBL25830857 0.91 PSMB5 (0.38) THRBALDH1A1HPGDNPC1LMNA
SCHEMBL13839881 0.90 THRB (0.40) THRBSMN1; SMN2KCNH2ALDH1A1HPGD
SCHEMBL12306919 0.89 THRB (0.35) THRBSMN1; SMN2ALDH1A1HPGDNPC1
SCHEMBL12255590 0.88 THRB (0.41) THRBSMN1; SMN2ALDH1A1HPGDNPC1
SCHEMBL1629356 0.88 THRB (0.40) THRBSMN1; SMN2KCNH2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9500967-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-9500967-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-20150099218-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-04-09 US disclosed
US-20150099218-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-04-09 US disclosed