SCHEMBL25830857

SCHEMBL25830857

C=CC(=O)OCc1ccc(N(c2ccccc2)c2ccc(-c3ccc(C)c(C)c3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.38
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
ENPP2 Q13822 3/20 0.37
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
MMP12 P39900 1/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
MCL1 Q07820 1/20 0.35
MGLL Q99685 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26531990 0.93 RAB9A (0.40) PSMB5NPC1RAB9AHCAR2ENPP2
SCHEMBL16625919 0.91 THRB (0.36) PSMB5NPC1RAB9AHCAR2ALDH1A1
SCHEMBL16625916 0.89 HCAR2 (0.45) NPC1RAB9AHCAR2ENPP2ALDH1A1
SCHEMBL13777455 0.89 HCAR2 (0.45) NPC1RAB9AHCAR2ENPP2ALDH1A1
SCHEMBL16625920 0.89 HCAR2 (0.45) NPC1RAB9AHCAR2ENPP2ALDH1A1
SCHEMBL12534114 0.89 HCAR2 (0.45) NPC1RAB9AHCAR2ENPP2ALDH1A1
SCHEMBL12727904 0.88 MMP12 (0.43) NPC1RAB9AHCAR2ENPP2ALDH1A1
SCHEMBL9915733 0.88 HCAR2 (0.44) NPC1RAB9AHCAR2ENPP2ALDH1A1
SCHEMBL25830863 0.88 PPARG (0.42) HSD17B1HSD17B2NPC1RAB9AHCAR2
SCHEMBL2602453 0.87 THRB (0.38) PSMB5NPC1RAB9AHCAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed