SCHEMBL16626286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16626282	0.97	TDP2 (0.42)	TDP2ALDH1A1ALOX15TDP1NPC1
	SCHEMBL16626117	0.89	ALOX15 (0.46)	TDP2ALDH1A1ALOX15TDP1NPC1
	SCHEMBL16626285	0.89	KIF11 (0.44)	TDP2ALDH1A1ALOX15TDP1KIF11
	SCHEMBL16626129	0.86	TDP1 (0.45)	TDP2ALDH1A1ALOX15TDP1NPC1
	SCHEMBL14252248	0.86	TDP2 (0.53)	TDP2ALDH1A1MEN1KMT2AMAPT
	SCHEMBL16626283	0.83	ALDH1A1 (0.38)	TDP2ALDH1A1ALOX15TDP1NPC1
	SCHEMBL17192488	0.82	ALOX15 (0.55)	TDP2ALDH1A1ALOX15TDP1NPC1
	SCHEMBL15641977	0.82	ALOX15 (0.55)	TDP2ALDH1A1ALOX15TDP1NPC1
	SCHEMBL308376	0.82	ALOX15 (0.55)	TDP2ALDH1A1ALOX15TDP1NPC1
	SCHEMBL29366467	0.82	ALOX15 (0.55)	TDP2ALDH1A1ALOX15TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.