Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663705 | 0.86 | SPR (0.34) | SPRELANEKMT2ANPSR1PLAT | |
| SCHEMBL1662835 | 0.85 | SMURF2 (0.37) | — | |
| SCHEMBL29155775 | 0.84 | ELANE (0.34) | SPRELANEKMT2ANPSR1PLAT | |
| SCHEMBL1663070 | 0.83 | SPR (0.32) | SPRSLC6A3PDE4BPLATALDH1A1 | |
| SCHEMBL1663533 | 0.83 | SPR (0.32) | SPRSLC6A3PDE4BPLATALDH1A1 | |
| SCHEMBL1662501 | 0.82 | HPGD (0.42) | SPRKMT2APLATALDH1A1MAPT | |
| SCHEMBL1663316 | 0.82 | SPR (0.34) | SPRSLC6A3PDE4BPLATLMNA | |
| SCHEMBL1662714 | 0.81 | SPR (0.33) | SPRSLC6A3PDE4BNPBWR1 | |
| SCHEMBL1665409 | 0.81 | SLC6A3 (0.40) | SLC6A3ELANEKMT2ANPSR1LMNA | |
| SCHEMBL1662717 | 0.81 | LIPG (0.36) | SPRPDE4BLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |