Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663316 | 0.85 | SPR (0.34) | SPRPDE4BSLC6A3CYP1A2POLB | |
| SCHEMBL1662717 | 0.83 | LIPG (0.36) | SPRPDE4BPOLBHPGD | |
| SCHEMBL1662681 | 0.81 | SPR (0.33) | SPRPDE4BSLC6A3NPBWR1 | |
| SCHEMBL1663070 | 0.80 | SPR (0.32) | SPRPDE4BSLC6A3 | |
| SCHEMBL1663533 | 0.80 | SPR (0.32) | SPRPDE4BSLC6A3 | |
| SCHEMBL1662501 | 0.79 | HPGD (0.42) | SPRCYP1A2POLBCYP2D6CYP2C9 | |
| SCHEMBL1665409 | 0.78 | SLC6A3 (0.40) | SLC6A3CYP1A2CYP2C9HPGD | |
| SCHEMBL1662940 | 0.77 | HIF1A (0.30) | NPBWR1 | |
| SCHEMBL1664392 | 0.75 | JAK1 (0.37) | SPR | |
| SCHEMBL1663215 | 0.75 | PDE4D (0.33) | SPRPDE4BSLC6A3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |