Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | TPH1 | P17752 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662681 | 0.83 | SPR (0.33) | SPRPDE4BSLC6A3PLATALDH1A1 | |
| SCHEMBL1663070 | 0.81 | SPR (0.32) | SPRACACBPDE4BSLC6A3PLAT | |
| SCHEMBL1662501 | 0.81 | HPGD (0.42) | SPRPLATALDH1A1 | |
| SCHEMBL1663316 | 0.81 | SPR (0.34) | SPRPDE4BSLC6A3PLATALDH1A1 | |
| SCHEMBL1662714 | 0.80 | SPR (0.33) | SPRPDE4BSLC6A3 | |
| SCHEMBL1665409 | 0.80 | SLC6A3 (0.40) | SLC6A3ALDH1A1 | |
| SCHEMBL1662717 | 0.79 | LIPG (0.36) | SPRPDE4B | |
| SCHEMBL1662940 | 0.78 | HIF1A (0.30) | — | |
| SCHEMBL1664392 | 0.77 | JAK1 (0.37) | SPR | |
| SCHEMBL1663215 | 0.77 | PDE4D (0.33) | SPRACACBPDE4BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |