Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18534153 | 0.78 | MAPT (0.39) | L3MBTL1 | |
| SCHEMBL24627874 | 0.77 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL17933364 | 0.73 | GRIA1 (0.42) | — | |
| SCHEMBL17933369 | 0.72 | ACHE (0.36) | L3MBTL1 | |
| SCHEMBL21165191 | 0.71 | L3MBTL1 (0.37) | L3MBTL1 | |
| SCHEMBL24628384 | 0.71 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL18183254 | 0.71 | ALDH1A1 (0.37) | L3MBTL1 | |
| SCHEMBL5732657 | 0.69 | L3MBTL1 (0.69) | L3MBTL1 | |
| SCHEMBL13826264 | 0.69 | — | — | |
| SCHEMBL3321065 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220134-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2022-07-14 | — | — | US | disclosed |
| US-10351581-B2 | Phosphohistidine mimetics and antibodies to same | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-07-16 | — | — | US | disclosed |
| US-20190092796-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-03-28 | — | — | US | disclosed |
| US-20160311838-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY | 2016-10-27 | — | — | US | disclosed |
| US-20160311838-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY | 2016-10-27 | — | — | US | disclosed |
| WO-2015051079-A2 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092796-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | PHPT1, CD4, CD81 | L3MBTL1 3410/4885PTPN11 251/4885PRMT5 408/4885 |
| US-20160311838-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | PHPT1, CD4, HCLS1 | L3MBTL1 4199/4885PTPN11 385/4885PRMT5 398/4885 |
| US-20220220134-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | PHPT1, CD4, CD81 | L3MBTL1 3410/4885PTPN11 251/4885PRMT5 408/4885 |
| US-10351581-B2 | Phosphohistidine mimetics and antibodies to same | PHPT1, CD4, HCLS1 | L3MBTL1 4199/4885PTPN11 385/4885PRMT5 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.