Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179099 | 0.85 | L3MBTL1 (0.53) | MAPTLMNACYP2C19KMT2AL3MBTL1 | |
| SCHEMBL24627874 | 0.80 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL18534183 | 0.80 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL17933331 | 0.78 | ACHE (0.38) | TDP1ALDH1A1 | |
| SCHEMBL17933369 | 0.75 | ACHE (0.36) | L3MBTL1 | |
| SCHEMBL18183254 | 0.74 | ALDH1A1 (0.37) | LMNAHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL17933364 | 0.73 | GRIA1 (0.42) | KMT2AKDM4E | |
| SCHEMBL24627873 | 0.69 | ACHE (0.46) | MAPTLMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL17459858 | 0.69 | — | — | |
| SCHEMBL21165191 | 0.68 | L3MBTL1 (0.37) | LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |