Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624740 | 0.88 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16627094 | 0.87 | SMN1; SMN2 (0.41) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16627090 | 0.86 | CYP1A2 (0.45) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16624737 | 0.82 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16624738 | 0.79 | L3MBTL1 (0.48) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16627091 | 0.75 | CYP1A2 (0.49) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16624692 | 0.74 | KMT2A (0.47) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL29488289 | 0.71 | ESR1 (0.56) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL602028 | 0.71 | ESR1 (0.56) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16624714 | 0.70 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051044-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |