Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241152 | 0.85 | LTA4H (0.52) | LTA4H | |
| Hydrochloric Acid SCHEMBL30186367 | 0.84 | LTA4H (0.50) | LTA4H | |
| SCHEMBL16627145 | 0.83 | LTA4H (0.41) | KMT2AHTTSMN1; SMN2LTA4H | |
| SCHEMBL16624686 | 0.79 | NPC1 (0.44) | GAAMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL19021001 | 0.77 | LTA4H (0.46) | KMT2AHTTSMN1; SMN2LTA4H | |
| SCHEMBL7753927 | 0.77 | CALM1 (0.50) | CYP1A2CYP3A4CYP2C19HIF1AKMT2A | |
| SCHEMBL20495588 | 0.77 | CALM1 (0.50) | CYP1A2CYP3A4CYP2C19HIF1AKMT2A | |
| SCHEMBL19020521 | 0.77 | KIF11 (0.50) | HTTSMN1; SMN2LTA4H | |
| SCHEMBL16624711 | 0.77 | GABRA1 (0.48) | SMN1; SMN2LTA4H | |
| SCHEMBL8361615 | 0.76 | MAPK1 (0.56) | GAAHTR1ADRD2CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051044-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |