Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624686 | 0.86 | NPC1 (0.44) | LTA4HNPC1RAB9AKIF11KCNH2 | |
| SCHEMBL16627140 | 0.84 | KIF11 (0.41) | LTA4HNPC1RAB9AKIF11SMN1; SMN2 | |
| SCHEMBL16627149 | 0.83 | GAA (0.48) | LTA4HSMN1; SMN2HTTKMT2A | |
| SCHEMBL19020521 | 0.82 | KIF11 (0.50) | LTA4HKIF11KCNH2SMN1; SMN2LMNA | |
| SCHEMBL28241152 | 0.81 | LTA4H (0.52) | LTA4HNPC1RAB9AKIF11KCNH2 | |
| SCHEMBL16624847 | 0.81 | CASP3 (0.50) | NPC1RAB9AKIF11KCNH2SMN1; SMN2 | |
| SCHEMBL16628094 | 0.81 | CYP11B1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAFFAR1 | |
| Hydrochloric Acid SCHEMBL30186367 | 0.80 | LTA4H (0.50) | LTA4HNPC1RAB9AKIF11KCNH2 | |
| SCHEMBL16624800 | 0.80 | MEN1 (0.42) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL17954315 | 0.80 | CASP3 (0.46) | NPC1RAB9ASMN1; SMN2FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051044-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |