Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 9/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627828 | 0.88 | PARP14 (0.52) | RXFP1PARP14KDM4EALDH1A1HPGD | |
| SCHEMBL16627691 | 0.80 | AHR (0.42) | RXFP1MAOBCYP2C9TRPV1NLRP3 | |
| SCHEMBL16627678 | 0.80 | PARP14 (0.52) | RXFP1PARP14KDM4EALDH1A1HPGD | |
| SCHEMBL16627681 | 0.80 | NPY5R (0.45) | RXFP1KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL16627760 | 0.79 | CCNA2 (0.45) | RXFP1PARP14KDM4EALDH1A1CYP2C9 | |
| SCHEMBL16627876 | 0.79 | RXFP1 (0.44) | RXFP1MAOBKDM4EMEN1KMT2A | |
| SCHEMBL16627890 | 0.78 | PARP14 (0.56) | RXFP1PARP14KDM4EALDH1A1CYP2C9 | |
| SCHEMBL16627592 | 0.76 | MT-CO2 (0.44) | PARP14KDM4EALDH1A1NLRP3MEN1 | |
| SCHEMBL16627692 | 0.75 | CNR1 (0.39) | RXFP1MAOBBCHEACHE | |
| SCHEMBL16627588 | 0.73 | AHR (0.41) | RXFP1MAOBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |