Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627665 | 0.90 | SMN1; SMN2 (0.51) | AHRGAASMN1; SMN2KDM4EHPGD | |
| SCHEMBL16627824 | 0.84 | MEN1 (0.47) | AHRGAASMN1; SMN2KDM4EHPGD | |
| SCHEMBL16627691 | 0.82 | AHR (0.42) | AHRMEN1KMT2A | |
| SCHEMBL16627588 | 0.80 | AHR (0.41) | AHRKDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL16627759 | 0.74 | NPY5R (0.47) | GAASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL16627803 | 0.74 | F10 (0.47) | AHRGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL16627754 | 0.74 | RAB9A (0.49) | AHRGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL16627823 | 0.73 | NPY5R (0.47) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL17183464 | 0.73 | SMN1; SMN2 (1.00) | GAASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL16627756 | 0.73 | AHR (1.00) | AHRMEN1KMT2ACNR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |