Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627823 | 0.85 | NPY5R (0.47) | NPY5RP2RX7MAPTMEN1KMT2A | |
| SCHEMBL16627665 | 0.85 | SMN1; SMN2 (0.51) | NPY5RP2RX7MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16627681 | 0.83 | NPY5R (0.45) | NPY5RP2RX7MAPTMEN1KMT2A | |
| SCHEMBL16627877 | 0.81 | MAPT (0.47) | P2RX7MAPTMEN1KMT2APOLB | |
| SCHEMBL16627880 | 0.74 | HDAC1 (0.47) | P2RX7MAPTMEN1KMT2APOLB | |
| SCHEMBL16627650 | 0.74 | AHR (0.56) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16627691 | 0.73 | AHR (0.42) | RAB9AMEN1KMT2APOLBNPC1 | |
| SCHEMBL16627588 | 0.71 | AHR (0.41) | NPY5RP2RX7RAB9AMEN1KMT2A | |
| SCHEMBL16627754 | 0.70 | RAB9A (0.49) | P2RX7MAPTRAB9AMEN1KMT2A | |
| SCHEMBL16627692 | 0.70 | CNR1 (0.39) | NPY5RP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |