Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627845 | 0.81 | KDM4E (0.39) | PARP14GAAALDH1A1KDM4EHPGD | |
| SCHEMBL16627855 | 0.79 | KDM4E (0.40) | PARP14ALDH1A1KDM4EHPGDHSP90AA1 | |
| SCHEMBL16627854 | 0.78 | KDM4E (0.39) | PARP14ALDH1A1KDM4EHPGDHSP90AA1 | |
| SCHEMBL16627760 | 0.75 | CCNA2 (0.45) | PARP14GAASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL16627825 | 0.74 | KMT2A (0.53) | PARP14GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL16627784 | 0.72 | ALDH1A1 (0.46) | PARP14GAAALDH1A1KDM4EHPGD | |
| SCHEMBL16627614 | 0.71 | PADI4 (0.39) | ALDH1A1KDM4EHSP90AA1HSP90AB1KMT2A | |
| SCHEMBL16627895 | 0.70 | MEN1 (0.58) | GAASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL16627610 | 0.69 | PADI4 (0.38) | ALDH1A1KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL16627650 | 0.69 | AHR (0.56) | GAASMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |