Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627787 | 0.81 | PARP14 (0.47) | ALDH1A1KDM4EOXTRKMT2ATP53 | |
| SCHEMBL16627896 | 0.81 | PARP1 (0.40) | MAPTALDH1A1KDM4EOXTRKMT2A | |
| SCHEMBL16627783 | 0.81 | PARP14 (0.47) | ALDH1A1KDM4EKMT2ATP53PARP14 | |
| SCHEMBL16627784 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EKMT2APARP14 | |
| SCHEMBL16627890 | 0.71 | PARP14 (0.56) | MAPTALDH1A1KDM4EKMT2APARP14 | |
| SCHEMBL15200885 | 0.69 | TP53 (0.44) | MAPTALDH1A1KDM4EOXTRKMT2A | |
| SCHEMBL16627845 | 0.69 | KDM4E (0.39) | MAPTALDH1A1KDM4ETP53PARP14 | |
| SCHEMBL16627854 | 0.67 | KDM4E (0.39) | ALDH1A1KDM4EPARP14NPC1 | |
| SCHEMBL16627893 | 0.67 | KMT2A (0.51) | MAPTALDH1A1KDM4ERECQLKMT2A | |
| SCHEMBL16627855 | 0.67 | KDM4E (0.40) | ALDH1A1KDM4EPARP14HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |