Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627787 | 0.93 | PARP14 (0.47) | PARP14ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL16627784 | 0.87 | ALDH1A1 (0.46) | PARP14ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL16627896 | 0.82 | PARP1 (0.40) | PARP14ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL16627626 | 0.81 | MAPT (0.47) | PARP14ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL15200885 | 0.80 | TP53 (0.44) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL16627777 | 0.77 | SMN1; SMN2 (0.58) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL16627855 | 0.73 | KDM4E (0.40) | PARP14ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL16627688 | 0.72 | MAPT (0.50) | ALDH1A1KDM4EKMT2AHPGDRAB9A | |
| SCHEMBL16627845 | 0.71 | KDM4E (0.39) | PARP14ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL16627596 | 0.70 | KMT2A (0.52) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |