Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627783 | 0.87 | PARP14 (0.47) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL16627787 | 0.82 | PARP14 (0.47) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL16627896 | 0.80 | PARP1 (0.40) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL16627626 | 0.79 | MAPT (0.47) | ALDH1A1KMT2AKDM4EHSD17B10MAPT | |
| SCHEMBL16627718 | 0.75 | MEN1 (0.64) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL16627680 | 0.72 | PARP14 (0.48) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL16627855 | 0.71 | KDM4E (0.40) | ALDH1A1HPGDKDM4EHSD17B10PARP14 | |
| SCHEMBL15200885 | 0.70 | TP53 (0.44) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL16627845 | 0.69 | KDM4E (0.39) | ALDH1A1HPGDKDM4EHSD17B10NPSR1 | |
| SCHEMBL16627869 | 0.69 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |