Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627877 | 0.78 | MAPT (0.47) | KMT2AMEN1P2RX7TP53SMN1; SMN2 | |
| SCHEMBL16627814 | 0.75 | F10 (0.48) | KMT2AMEN1ATMTP53RXFP1 | |
| SCHEMBL16627876 | 0.74 | RXFP1 (0.44) | KMT2AMEN1TP53RXFP1RAB9A | |
| SCHEMBL16627681 | 0.70 | NPY5R (0.45) | KMT2AMEN1P2RX7RXFP1SMN1; SMN2 | |
| SCHEMBL16627691 | 0.69 | AHR (0.42) | KMT2AMEN1RXFP1RAB9AMAOB | |
| SCHEMBL16627759 | 0.69 | NPY5R (0.47) | KMT2AMEN1P2RX7TP53SMN1; SMN2 | |
| SCHEMBL16627880 | 0.69 | HDAC1 (0.47) | KMT2AMEN1P2RX7TP53SMN1; SMN2 | |
| SCHEMBL16627749 | 0.68 | MEN1 (0.58) | KMT2AMEN1P2RX7TP53RXFP1 | |
| SCHEMBL16627588 | 0.67 | AHR (0.41) | KMT2AMEN1P2RX7TP53RXFP1 | |
| SCHEMBL16627803 | 0.66 | F10 (0.47) | KMT2AMEN1P2RX7TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |