Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627816 | 0.79 | P2RX7 (0.48) | MAPTTP53P2RX7RXFP1AHR | |
| SCHEMBL16627878 | 0.79 | P2RX7 (0.49) | MAPTTP53P2RX7KDM4E | |
| SCHEMBL16627692 | 0.74 | CNR1 (0.39) | P2RX7CNR1CNR2NPY5RRXFP1 | |
| SCHEMBL16627759 | 0.70 | NPY5R (0.47) | MAPTTP53P2RX7NPY5RKDM4E | |
| SCHEMBL16627576 | 0.67 | P2RX7 (0.43) | MAPTP2RX7CNR1CNR2LMNA | |
| SCHEMBL16627688 | 0.66 | MAPT (0.50) | MAPTNPY5RKDM4E | |
| SCHEMBL16627823 | 0.66 | NPY5R (0.47) | MAPTTP53P2RX7NPY5RKDM4E | |
| SCHEMBL16627665 | 0.66 | SMN1; SMN2 (0.51) | P2RX7CNR1CNR2NPY5RAHR | |
| SCHEMBL16627681 | 0.65 | NPY5R (0.45) | MAPTP2RX7NPY5RRXFP1KDM4E | |
| SCHEMBL23652963 | 0.64 | MAPT (0.79) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |