Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627678 | 0.82 | PARP14 (0.52) | MAPTGAAKMT2APOLBSMN1; SMN2 | |
| SCHEMBL16627819 | 0.82 | BRD4 (0.54) | MAPTKMT2APOLBRAB9ANPC1 | |
| SCHEMBL16627890 | 0.80 | PARP14 (0.56) | MAPTKMT2APOLBRAB9ANPC1 | |
| SCHEMBL16627818 | 0.77 | RXFP1 (0.53) | MAPTKMT2AMMP2MMP9MMP8 | |
| SCHEMBL16627817 | 0.77 | KMT2A (0.51) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16627828 | 0.75 | PARP14 (0.52) | MAPTGAAHTTKMT2APOLB | |
| SCHEMBL16627760 | 0.73 | CCNA2 (0.45) | GAAKMT2APOLBSMN1; SMN2KDM4E | |
| SCHEMBL16627690 | 0.73 | RXFP1 (0.40) | MAPTGAAKMT2ARAB9ANPC1 | |
| SCHEMBL16627783 | 0.72 | PARP14 (0.47) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16627806 | 0.71 | NHERF1 (0.49) | MAPTGAAKMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |