Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627828 | 0.81 | PARP14 (0.52) | GAAKDM4EMEN1KMT2APARP14 | |
| SCHEMBL16627678 | 0.81 | PARP14 (0.52) | GAAKDM4EMEN1KMT2APARP14 | |
| SCHEMBL16627710 | 0.79 | KMT2A (0.52) | GAAKDM4EMEN1KMT2APARP14 | |
| SCHEMBL16627690 | 0.79 | RXFP1 (0.40) | GAAKDM4EMEN1KMT2APARP14 | |
| SCHEMBL16627890 | 0.79 | PARP14 (0.56) | KDM4EMEN1KMT2AHSD17B10PARP14 | |
| SCHEMBL16627680 | 0.75 | PARP14 (0.48) | GAACASP3KDM4EMEN1KMT2A | |
| SCHEMBL16627688 | 0.73 | MAPT (0.50) | GAAKDM4EKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16627650 | 0.71 | AHR (0.56) | GAACASP3KDM4EMEN1KMT2A | |
| SCHEMBL16627806 | 0.70 | NHERF1 (0.49) | GAAKDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL16627588 | 0.70 | AHR (0.41) | KDM4EMEN1KMT2ARXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |