Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627717 | 0.75 | P2RX7 (0.48) | P2RX7P2RX4KMT2AMEN1TP53 | |
| SCHEMBL16627673 | 0.71 | P2RX7 (0.48) | P2RX7P2RX4TP53HDAC1HDAC11 | |
| SCHEMBL16627627 | 0.69 | P2RX7 (0.51) | P2RX7P2RX4ALDH1A1GAAKMT2A | |
| SCHEMBL16627667 | 0.69 | P2RX7 (0.47) | P2RX7P2RX4KMT2AMEN1TP53 | |
| SCHEMBL16627867 | 0.69 | P2RX7 (0.52) | P2RX7P2RX4ALDH1A1GAATP53 | |
| SCHEMBL16627865 | 0.67 | P2RX7 (0.58) | P2RX7P2RX4KMT2AMEN1 | |
| SCHEMBL16627864 | 0.66 | P2RX7 (0.60) | P2RX7P2RX4TP53HDAC1 | |
| SCHEMBL16627629 | 0.65 | P2RX7 (0.60) | P2RX7P2RX4ALDH1A1KMT2AMEN1 | |
| SCHEMBL16627628 | 0.65 | P2RX7 (0.67) | P2RX7P2RX4HDAC1HDAC11HDAC8 | |
| SCHEMBL16627911 | 0.65 | P2RX7 (0.51) | P2RX7P2RX4HDAC1HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |