SCHEMBL16627976

SCHEMBL16627976

CC(=O)C/C(C)=N/c1ccccc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 6/20 0.38
HSD17B10 Q99714 2/20 0.38
CFTR P13569 1/20 0.38
KDM4E B2RXH2 6/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GRIN2D O15399 2/20 0.37
GRIN3B O60391 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN2C Q14957 2/20 0.37
GRIN3A Q8TCU5 2/20 0.37
SIGMAR1 Q99720 2/20 0.37
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16628008 0.80 KDM4E (0.43) GAANPC1RAB9AKMT2AMEN1
SCHEMBL14792742 0.80 SIGMAR1 (0.50) GAANPC1RAB9AKMT2AMEN1
SCHEMBL15224520 0.76 SCN2A (0.48) KMT2AMEN1ALDH1A1KDM4EGRIN2D
SCHEMBL15224521 0.76 SCN2A (0.48) KMT2AMEN1ALDH1A1KDM4EGRIN2D
SCHEMBL12568931 0.74 GAA (0.54) GAANPC1RAB9AL3MBTL1KMT2A
SCHEMBL347753 0.73 NOS1 (0.50) NPC1RAB9AL3MBTL1ALDH1A1HSD17B10
SCHEMBL5680219 0.73 NOS1 (0.50) NPC1RAB9AL3MBTL1ALDH1A1HSD17B10
SCHEMBL347754 0.73 NOS1 (0.50) NPC1RAB9AL3MBTL1ALDH1A1HSD17B10
SCHEMBL17489129 0.73 RECQL (0.43) RAB9AKMT2AMEN1ALDH1A1HSD17B10
SCHEMBL21192659 0.72 LMNA (0.37) KMT2AMEN1KDM4EGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
WO-2015050583-A1 METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2015-04-09 WO disclosed