SCHEMBL16628008

SCHEMBL16628008

CC(=O)C/C(C)=N/c1ccccc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.43
MAPT P10636 6/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
HTT P42858 2/20 0.43
NPC1 O15118 2/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 6/20 0.40
RAB9A P51151 2/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MPO P05164 1/20 0.37
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
THRB P10828 1/20 0.36
TSHR P16473 1/20 0.36
IAPP P10997 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14792742 0.81 SIGMAR1 (0.50) KDM4ESMN1; SMN2KMT2AMEN1HTT
SCHEMBL16627976 0.80 GAA (0.42) KDM4EMAPTSMN1; SMN2KMT2AMEN1
SCHEMBL15224520 0.77 SCN2A (0.48) KDM4EKMT2AMEN1ALDH1A1TDP1
SCHEMBL14482825 0.77 THRB (0.48) KDM4EMAPTSMN1; SMN2KMT2AMEN1
SCHEMBL14482828 0.77 THRB (0.48) KDM4EMAPTSMN1; SMN2KMT2AMEN1
SCHEMBL15224521 0.77 SCN2A (0.48) KDM4EKMT2AMEN1ALDH1A1TDP1
Catechol SCHEMBL21296992 0.75 KDM4E (0.53) KDM4EMAPTSMN1; SMN2KMT2AMEN1
SCHEMBL17489129 0.75 RECQL (0.43) KDM4EMAPTSMN1; SMN2KMT2AMEN1
SCHEMBL5680219 0.75 NOS1 (0.50) MAPTSMN1; SMN2HTTNPC1RAB9A
SCHEMBL347754 0.75 NOS1 (0.50) MAPTSMN1; SMN2HTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
WO-2015050583-A1 METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2015-04-09 WO disclosed