Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547718 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTRECQLGAACRHBP | |
| SCHEMBL9509221 | 0.82 | CRHBP (0.54) | ALDH1A1MAPTRECQLGAACRHBP | |
| SCHEMBL7997158 | 0.82 | CRHBP (0.54) | ALDH1A1MAPTRECQLGAACRHBP | |
| SCHEMBL1700747 | 0.81 | CRHBP (0.53) | ALDH1A1MAPTRECQLGAACRHBP | |
| SCHEMBL21728986 | 0.81 | CRHBP (0.53) | ALDH1A1MAPTRECQLGAACRHBP | |
| SCHEMBL4301791 | 0.81 | CRHBP (0.56) | ALDH1A1MAPTGAACRHBPCRHR2 | |
| SCHEMBL8742128 | 0.81 | CRHBP (0.56) | ALDH1A1MAPTGAACRHBPCRHR2 | |
| SCHEMBL1700749 | 0.81 | CRHBP (0.53) | ALDH1A1MAPTRECQLGAACRHBP | |
| SCHEMBL21626406 | 0.79 | CRHBP (0.57) | ALDH1A1MAPTGAACRHBPCRHR2 | |
| SCHEMBL6129749 | 0.79 | CRHBP (0.57) | ALDH1A1MAPTGAACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11852633-B2 | Compositions and methods for analyzing cysteine | GEORGETOWN UNIVERSITY (US) | 2023-12-26 | — | — | US | disclosed |
| US-20230160903-A1 | COMPOSITIONS AND METHODS FOR ANALYZING CYSTEINE | NATIONAL SCIENCE FOUNDATION | 2023-05-25 | — | — | US | disclosed |
| US-11635436-B2 | Compositions and methods for analyzing cysteine | GEORGETOWN UNIVERSITY (US) | 2023-04-25 | — | — | US | disclosed |
| US-20200150128-A1 | COMPOSITIONS AND METHODS FOR ANALYZING CYSTEINE | NATIONAL SCIENCE FOUNDATION | 2020-05-14 | — | — | US | disclosed |
| US-10188727-B2 | Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus | YALE UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| WO-2018200498-A1 | COMPOSITIONS AND METHODS FOR ANALYZING CYSTEINE | GEORGETOWN UNIVERSITY (US) | 2018-11-01 | — | — | WO | disclosed |
| US-20160082102-A1 | BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS | UNIV YALE (US) | 2016-03-24 | — | — | US | disclosed |
| WO-2011046946-A2 | BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS | YALE UNIVERSITY (US) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11852633-B2 | Compositions and methods for analyzing cysteine | CTH, CBS, GCLC | ALDH1A1 2971/4885MAPT 3873/4885RECQL 2933/4885 |
| US-11635436-B2 | Compositions and methods for analyzing cysteine | CTH, CBS, GCLC | ALDH1A1 2971/4885MAPT 3873/4885RECQL 2933/4885 |
| US-20200150128-A1 | COMPOSITIONS AND METHODS FOR ANALYZING CYSTEINE | CTH, CBS, GCLC | ALDH1A1 2971/4885MAPT 3873/4885RECQL 2933/4885 |
| US-20230160903-A1 | COMPOSITIONS AND METHODS FOR ANALYZING CYSTEINE | CTH, CBS, GCLC | ALDH1A1 2971/4885MAPT 3873/4885RECQL 2933/4885 |
| US-20160082102-A1 | BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS | CD4, HAVCR2, CD2 | ALDH1A1 4530/4885MAPT 1075/4885RECQL 4627/4885 |
| US-10188727-B2 | Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus | CD4, HAVCR2, CD2 | ALDH1A1 4530/4885MAPT 1075/4885RECQL 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.