Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628263 | 0.88 | POLB (0.56) | CHRM1MAPTHTTCNR2 | |
| SCHEMBL22001753 | 0.85 | POLB (0.53) | CHRM1MAPTHTT | |
| SCHEMBL20531421 | 0.84 | CHRM1 (0.52) | ADRA1DCHRM1 | |
| SCHEMBL16628260 | 0.84 | CHRM1 (0.46) | ADRA1DCHRM1CNR2 | |
| SCHEMBL16628324 | 0.83 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL16628329 | 0.82 | CHRM1 (0.44) | CHRM1 | |
| SCHEMBL22001755 | 0.81 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL16628328 | 0.80 | RPS6KB1 (0.54) | CHRM1HTTNPSR1 | |
| SCHEMBL18011014 | 0.80 | CHRM1 (0.43) | ADRA1DCHRM1KDM4ECNR2 | |
| SCHEMBL22001176 | 0.80 | ALDH1A1 (0.48) | CHRM1MAPTHTTNPSR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049574-A1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-09 | — | — | WO | disclosed |