Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607561 | 0.98 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL18065079 | 0.97 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL345585 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16628478 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16628613 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Lithium Ion SCHEMBL16628565 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16628435 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Potassium Ion SCHEMBL18140860 | 0.95 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| Potassium Ion SCHEMBL4575490 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| Potassium Ion SCHEMBL31302972 | 0.93 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080304-A | Surface charged polymer nano particle and its synthesis method and application | — | 2026-05-26 | — | — | CN | claimed |
| CN-119708613-B | Polymer porous membrane for fluorescent pattern transfer printing and preparation method and application thereof | 四川大学 | 2026-05-19 | — | — | CN | claimed |
| US-12595396-B2 | Acid resistant filter media | ENTEGRIS, INC. (US) | 2026-04-07 | — | — | US | claimed |
| US-20260062367-A1 | EVOLVING RANDOM HETEROPOLYMERS TOWARDS CATALYTICALLY ACTIVE MATERIALS | MASSACHUSETTS INST TECHNOLOGY (US) | 2026-03-05 | — | — | US | claimed |
| US-20260043111-A1 | EXTRACTION OF CRITICAL MINERALS USING POLYANIONS | UNIV KANSAS (US) | 2026-02-12 | — | — | US | claimed |
| WO-2025260204-A1 | CROSSLINKED HYDROGELS WITH CONTROLLED PERMEABILITY | ALLARTA LIFE SCIENCE INC. (CA) | 2025-12-26 | — | — | WO | claimed |
| WO-2025260203-A1 | CLICK CHEMISTRY POLYMER HYDROGELS | ALLARTA LIFE SCIENCE INC. (CA) | 2025-12-26 | — | — | WO | claimed |
| WO-2025260202-A1 | AIR PRINTING OF HYDROGELS | ALLARTA LIFE SCIENCE INC. (CA) | 2025-12-26 | — | — | WO | claimed |
| EP-4084830-B1 | BIOACTIVE PLASTICS WITH PROGRAMMABLE DEGRADATION AND MICROPLASTIC ELIMINATION | UNIV CALIFORNIA (US) | 2025-12-10 | — | — | EP | claimed |
| US-12454501-B2 | Evolving random heteropolymers towards catalytically active materials | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-10-28 | — | — | US | claimed |
| EP-1409629-B1 | USE OF GRAFT POLYMERS IN FABRIC CLEANING | UNILEVER PLC (GB) | 2005-10-19 | — | — | EP | claimed |
| US-20040176534-A1 | Polymers and their synthesis | Henkel IP & Holding GmbH (DE) | 2004-09-09 | — | — | US | claimed |
| EP-1414867-A1 | POLYMERS AND THEIR SYNTHESIS | UNILEVER PLC (GB) | 2004-05-06 | — | — | EP | claimed |
| EP-1409629-A1 | USE OF GRAFT POLYMERS IN FABRIC CLEANING | UNILEVER PLC (GB) | 2004-04-21 | — | — | EP | claimed |
| WO-2003010206-A1 | POLYMERS AND THEIR SYNTHESIS | UNILEVER PLC (GB) | 2003-02-06 | — | — | WO | claimed |
| WO-2003010267-A1 | USE OF POLYMERS IN FABRICS CLEANING | UNILEVER PLC (GB) | 2003-02-06 | — | — | WO | claimed |
| US-5368781-A | Narrow band radiation filter films | CYTEC TECHNOLOGY CORP. (US) | 1994-11-29 | — | — | US | claimed |
| US-5342552-A | Narrow band radiation filter films | CYTEC TECHNOLOGY CORP. (US) | 1994-08-30 | — | — | US | claimed |
| US-5330685-A | Narrow band radiation filter films | AMERICAN CYANAMID COMPANY (US) | 1994-07-19 | — | — | US | claimed |
| US-5266238-A | Anionic polymer latex particles in crosslinked acrylamide polymer hydrogel | AMERICAN CYANAMID COMPANY (US) | 1993-11-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260043111-A1 | EXTRACTION OF CRITICAL MINERALS USING POLYANIONS | SLC39A14, PARG, CA2 | TSHR 2427/4885THRB 3035/4885POLB 1871/4885 |
| US-20260062367-A1 | EVOLVING RANDOM HETEROPOLYMERS TOWARDS CATALYTICALLY ACTIVE MATERIALS | ESD, TET2, HPD | TSHR 1631/4885THRB 1625/4885POLB 339/4885 |
| US-12454501-B2 | Evolving random heteropolymers towards catalytically active materials | PNKP, MGAM, HMBS | TSHR 4701/4885THRB 3835/4885POLB 52/4885 |
| US-12595396-B2 | Acid resistant filter media | SDC2, F7, SDC1 | TSHR 647/4885THRB 2672/4885POLB 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.