SCHEMBL6575706

SCHEMBL6575706

CCc1ccccc1C(O)=S

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
CLCN2 P51788 1/20 0.44
HTT P42858 2/20 0.44
ALDH1A1 P00352 3/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 2/20 0.40
FOLH1 Q04609 1/20 0.39
TSHR P16473 1/20 0.39
TP53 P04637 1/20 0.39
ALOX15 P16050 1/20 0.39
ABCC1 P33527 1/20 0.39
ALOX12 P18054 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
F2R P25116 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL22325701 0.92 CLCN2 (0.40) GABRA1GABRB2CLCN2HTTALDH1A1
SCHEMBL11430114 0.83 KMT2A (0.43) HTTALDH1A1GAAMAPTKMT2A
Thiobenzoic Acid SCHEMBL21633389 0.82 CES2 (0.44) HTTALDH1A1MAPTKMT2ATP53
SCHEMBL28554650 0.81 GABRA1 (0.45) GABRA1GABRB2CLCN2HTTALDH1A1
SCHEMBL1830469 0.81 GABRA1 (0.45) GABRA1GABRB2CLCN2HTTALDH1A1
SCHEMBL28423659 0.81 CLCN2 (0.41) GABRA1GABRB2CLCN2HTTALDH1A1
SCHEMBL166286 0.80 GABRA1 (0.43) GABRA1GABRB2CLCN2HTTALDH1A1
SCHEMBL11443422 0.80 GABRA1 (0.43) GABRA1GABRB2CLCN2HTTALDH1A1
SCHEMBL6894755 0.80 GAA (0.46) GABRA1GABRB2CLCN2ALDH1A1GAA
SCHEMBL9791249 0.79 LIPG (0.46) HTTKMT2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590734-A Method for synthesizing 2-methyl-4H-benzo [ d ] [1,3] oxathiacyclohexadiene-4-one 常州大学 2019-12-20 CN claimed
EP-2699606-B1 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORP (JP) 2016-09-28 EP claimed
EP-2699606-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP Bridgestone Corporation (JP) 2014-02-26 EP claimed
US-20140018500-A1 Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group BRIDGESTONE CORPORATION (JP) 2014-01-16 US claimed
WO-2012135451-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-10-04 WO claimed
US-5466858-A Ruthenium catalyst, high selectivity with a carboxylic acid UBE INDUSTRIES, LTD. (JP) 1995-11-14 US claimed
JP-54144331-A None JP disclosed
WO-2023225558-A1 INHIBITORS OF RLIP76 AVESTA76 THERAPEUTICS, INC. (US) 2023-11-23 WO disclosed
CN-109476616-B Piperazinyl methanone NAAA inhibitors 加利福尼亚大学董事会 2023-10-13 CN disclosed
CN-110590734-B Method for synthesizing 2-methyl-4H-benzo [ d ] [1,3] oxathiacyclohexadiene-4-one 常州大学 2022-03-25 CN disclosed
CN-110590734-B Method for synthesizing 2-methyl-4H-benzo [ d ] [1,3] oxathiacyclohexadiene-4-one 常州大学 2022-03-25 CN disclosed
CN-107072206-B Pesticidal compositions and related methods 美国陶氏益农公司 2020-02-21 CN disclosed
CN-110590734-A Method for synthesizing 2-methyl-4H-benzo [ d ] [1,3] oxathiacyclohexadiene-4-one 常州大学 2019-12-20 CN disclosed
US-6562936-B1 Resin excellent in hydrolysis and heat stability such as a reduction in molecular weight at the time of molding and color retention and moldability such as releasability and transferability, rarely experiences residence deterioration TEIJIN LIMITED (JP) 2003-05-13 US disclosed
US-6509435-B1 Heat resistance, stability; moldings TEIJIN LIMITED (JP) 2003-01-21 US disclosed
EP-1191049-A1 POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-03-27 EP disclosed
EP-1120435-A1 APPARATUS AND METHOD FOR PRODUCING RESIN TEIJIN LIMITED (JP) 2001-08-01 EP disclosed
US-5466858-A Ruthenium catalyst, high selectivity with a carboxylic acid UBE INDUSTRIES, LTD. (JP) 1995-11-14 US disclosed
US-5411977-A Substituted 2,5-diaryl-4-isothiazolin-3-ones as antiinflammatory and antithrombotic agents THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1995-05-02 US disclosed
JP-S54144331-A P'-CYANOPHENYL P-(BETA-ALKOXY)ETHYLTHIO-BENZOATE CHISSO CORP 1979-11-10 JP disclosed