Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.36 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.36 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.36 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.36 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.36 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.36 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | RECQL | P46063 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2166808 | 0.76 | CES2 (0.47) | KDM4EMAPTALOX15HSD17B10ALDH1A1 | |
| SCHEMBL2165459 | 0.72 | CA12 (0.45) | TERTKDM4EMAPTRECQLDBH | |
| SCHEMBL2167670 | 0.71 | KDM4E (0.41) | SELLSELPHDAC1KDM4EMAPT | |
| SCHEMBL2166768 | 0.67 | MAPT (0.48) | KDM4EMAPTALOX15HSD17B10RECQL | |
| SCHEMBL2167651 | 0.67 | CES2 (0.45) | KDM4EMAPTALOX15HSD17B10ALDH1A1 | |
| SCHEMBL2166868 | 0.64 | ALDH1A1 (0.37) | KDM4EMAPTALOX15HSD17B10RECQL | |
| SCHEMBL2166642 | 0.64 | CA1 (0.38) | KDM4EMAPTRECQLALDH1A1HPGD | |
| SCHEMBL1063407 | 0.64 | SELL (0.68) | SELLSELPHDAC1PIK3CATERT | |
| SCHEMBL77708 | 0.62 | SELL (1.00) | SELLSELPHDAC1PIK3CAKDM4E | |
| SCHEMBL6858983 | 0.62 | SELL (0.65) | SELLSELPHDAC1PIK3CATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |