Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA7 | P43166 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 3/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2166899 | 0.82 | MEN1 (0.54) | KDM4EGAAMAPTPOLBHDAC6 | |
| SCHEMBL2314061 | 0.82 | MEN1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2167670 | 0.80 | KDM4E (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2166768 | 0.80 | MAPT (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3388283 | 0.78 | MEN1 (0.43) | KDM4EGAAMAPTPOLBPTGS2 | |
| SCHEMBL2164877 | 0.77 | CES2 (0.48) | KDM4EMAPT | |
| SCHEMBL2166261 | 0.74 | HSP90AA1 (0.46) | CA1CA2MAPT | |
| SCHEMBL2166342 | 0.74 | TSHR (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2166868 | 0.74 | ALDH1A1 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2166642 | 0.73 | CA1 (0.38) | CA1CA2KDM4EMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | claimed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | claimed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | claimed |
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | disclosed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | disclosed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | disclosed |
| EP-2350036-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | Pierre Fabre Dermo-Cosmétique (FR) | 2011-08-03 | — | — | EP | disclosed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | disclosed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | disclosed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | disclosed |
| WO-2010034827-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010034827-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | NQO1, ESD, DHPS | CA12 4790/4885CA1 4786/4885CA2 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.