Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | FUT4 | P22083 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2166642 | 0.84 | CA1 (0.38) | KDM4EALDH1A1MAPTCA1CA2 | |
| SCHEMBL2165459 | 0.80 | CA12 (0.45) | KDM4ESNCAMAPTCA12CA1 | |
| SCHEMBL2314061 | 0.78 | MEN1 (0.47) | KDM4ESNCAALDH1A1MAPTCA12 | |
| SCHEMBL2166822 | 0.78 | PKM (0.49) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL2166768 | 0.75 | MAPT (0.48) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL2166868 | 0.72 | ALDH1A1 (0.37) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL2166899 | 0.71 | MEN1 (0.54) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL2167245 | 0.71 | TPMT (0.44) | KDM4ELMNAALDH1A1MAPTCA9 | |
| SCHEMBL16628800 | 0.71 | SELL (0.44) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL2166808 | 0.69 | CES2 (0.47) | KDM4ELMNATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | claimed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | claimed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | claimed |
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | disclosed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | disclosed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | disclosed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | disclosed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | disclosed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | disclosed |
| WO-2010034827-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010034827-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | NQO1, ESD, DHPS | KDM4E 243/4885LMNA 1547/4885TDP1 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.